(for veterinary information only)
BRAND NAMES: BONINE, ANTIVERT, DRAMAMINE, UNIVERT, VERTIN-21
Motion sickness is an important problem for many pets and while the commonly prescribed acepromazine has many benefits as an anti-nausea drug its long-acting tranquilizing properties make it inconvenient for short trips. Fortunately, there are more appropriate alternatives. Ideally, for short-term relief of carsickness, we would like a medication with minimal side effects, that does not yield long lasting drowsiness, and is conveniently dosed. Although meclizine hydrochloride is a human medication, it has proved to be quite helpful for relief of nausea in our pets.
HOW THIS MEDICATION IS USED
Meclizine hydrochloride is generally used for nausea relief due to motion sickness. It is also used to control the nausea resulting from vestibular disease, a syndrome characterized by vertigo and loss of balance.
For the prevention of motion sickness, meclizine hydrochloride should be given approximately 30 minutes before travel. Anti-nauseal effects can be expected to last approximately 6 hours.
Meclizine hydrochloride is a member of the piperazine class of antihistamines. It may produce some drowsiness though nothing like the 6 to 8 hours of tranquilization yielded by its cousin, acepromazine.
Most antihistamines have potential to cause any of a group of symptoms referred to as anticholinergic symptoms: urinary retention, dry mouth, increased heart rate, and exacerbation of glaucoma (elevated pressure within the eye). It may also reduce the ability to produce milk in lactating mothers.
INTERACTIONS WITH OTHER DRUGS
Meclizine hydrochloride should not be given in conjunction with other tranquilizing drugs as such a combination may lead to excess sedation.
CONCERNS AND CAUTIONS
Page last updated: 2/5/2016