Mar Vista Animal Medical Center

3850 Grand View Blvd.
Los Angeles, CA 90066



(“Water on the Brain”)

The brain and spinal cord are bathed in cerebrospinal fluid (the fluid that is tapped and analyzed when a“spinal tap” is performed). This fluid is created in special chambers in the brain called “ventricles.” It circulates around the brain and spinal cord without ever mixing with the bloodstream and is ultimately reabsorbed back into the body.

In hydrocephalus, there is too much fluid, either because of a drainage problem or an over-production problem. When the problem is congenital (meaning the animal is born with the condition or born so as to promptly develop the condition), the skull is still soft enough at birth and in infancy to expand somewhat with the extra fluid inside the brain. This expansion leads to a dome-shaped head and frequently an open fontanelle (soft spot where the skull bones have not fully closed).

Unfortunately, when the skull bones eventually harden, the shape of the skull is set and there is no more room to accommodate the increasing fluid volume inside. Pressure on the brain results and therein lies the problem. Because the skull cannot expand with increased contents, the result is compression of the brain by the extra fluid.

Child with Hydrocephalus
(Photocredit: Public Domain Image)

Puppy with Hydrocephalus
(original graphic by



Most animals with hydrocephalus are puppies with congenital anomalies leading to hydrocephalus (they are not born with hydrocephalus but they are born with the anatomical problems that quickly lead to hydrocephalus). The most commonly affected breeds are those with a natural tendency towards the domed-head: Chihuahua, Pomeranian, Yorkshire terrier, English bulldog, Lhasa apso, Pug, Pekingese, Boston terrier, Maltese, toy poodle, and Cairn terrier).



Yorkshire Terrier

English Bulldog

Lhasa apso



Boston terrier



Cairn terrier


The same configuration that produces the domed head in infancy causes a fusing of the area of the brain called the "rostral colliculi." The fusion the colliculi narrows the ducts that carry the cerebrospinal fluid impeding normal flow. Fluid leaks into the white matter of the brain causing edema or, worse, the fluid actually compresses the developing brain. In puppies, this is generally genetic problem related to the breed. In the kitten, however, the most common cause is exposure during the mother cat's pregnancy either to the drug griseofulvin (used to treat the ringworm fungus) or to the feline distemper virus.

While we usually think of hydrocephalus as a young baby's problem, hydrocephalus can also be acquired in adulthood when inflammatory brain disease causes swelling and obstructs the flow channels of the cerebrospinal fluid.



When a puppy or kitten has hydrocephalus symptoms usually become evident by 8-12 weeks of age. The skull looks especially round and there is an open fontanelle (“skull soft spot”) on the top of the head. The pet may show what is called the “setting sun” sign which means the eyes are directed downwards (and possibly outwards). The animal may suffer from seizures (less than 20% of affected puppies), blindness, may press the head into corners, may walk in circles, have mental dullness or have extreme difficulty in house-training (over 75%).

That said, many dome-headed babies have open fontanelles and never develop any neurologic deficits and never require treatment. The key to diagnosis is about the behavior and mental development of the baby. If there is a domed head and open fontanelle AND a setting sun sign, mental dullness, learning disability, or overt neurologic symptoms then further action is necessary.


(original graphic by

(Photocredit: Steve Weaver via Wikimedia Commons)

The drawing shows a puppy with the "setting sun sign." Note the irises are positioned low, like
a sun dipping partly below the horizon. This is an indicator of increased intracranial pressure.




Radiograph of a hydrocephalic puppy.
Note the unusually domed head and thin skull bones.
(original graphic by

Radiographs of the skull will show thin skull bones but to truly confirm the condition imaging of the brain is needed. This can be done with special imaging such as CT, MRI, or even directing ultrasound through the open fontanelle. The size of the brain ventricles is examined and the presence of edema in the white matter is checked. If it is ultimately decided that the baby truly has a neurologic problem and all the signs of excessive cerebrospinal fluid are evident then treatment can be pursued.



Temporary relief of the increased fluid pressure can be achieved with medication. Diuretics can be used to decrease fluid production in the brain but one must be careful about causing the patient to become dehydrated. Electrolyte imbalances are also possible with prolonged diuretic use. Oddly, the antacid omeprazole has been shown to decrease cerebrospinal fluid production by 26% though we do not know how this occurs. Some studies have not shown benefit so it is unclear how well this works or if specific circumstances are necessary. Corticosteroids such as prednisone can relieve swelling in the brain and have become the center of medical therapy.

For a more permanent resolution, a shunt must be surgically placed. A shunt is a small tube that is surgically implanted in one of the brain’s ventricles. It siphons excess fluid away and drains it to another area of the body where it is harmless (such as the abdominal cavity). As the animal grows, “shunt revisions” are required to re-fit the shunt. If there is evidence of infection in the central nervous system, a shunt cannot be placed. This is because the placement of a foreign body (i.e. the shunt itself) will provide a shelter for the infection and the infection will never clear. The infection must be resolved before shunt placement.

Complications of the shunt include: infection (4-10% of all shunts placed in humans get infected), over-drainage, or under-drainage/obstruction of the tubing. The shunt can drain to either the abdominal cavity or heart. Fewer complications (as well as easier placement) are associated with shunts that go to the abdomen. Overall, success rate for the ventriculoperitoneal shunt is felt to be approximately 80%. That said, in 2019 Gillespie et al published a retrospective study on 38 dogs with hydrocephalus. Of the 26 dogs receiving shunts, 14 improved, 1 stabilized, and 11 deteriorated. Of the 12 dogs treated only with medication, 6 improved and 6 deteriorated.


Shunt placement is a specialized procedure. Expect to see either a surgery specialist or neurologist for this procedure.



There are several support group for hydorcephalus pet owners:

To Find a Veterinary Neurologist:


Page last updated: 7/28/2022